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has elegantly demonstrated that NRF2 is a key suppressor of ILC2 activation, our study provides the missing upstream link, identifying melatonin, a canonical circadian hormone, as a critical activator of the NRF2-Glutathione axis in ILC2s (64)

Lineage tracing of selected transgenic mouse mutants has shown the NOTCH, PI3K, TRP53 pathways to be critical regulators of esophageal progenitors 33,34,37